Generating DNA Origami Nanostructures through Shape Annealing

Structural DNA nanotechnology involves the design and self-assembly of DNA-based nanostructures. As a field, it has progressed at an exponential rate over recent years. The demand for unique origami nanostructures driven development tools, but current CAD tools structural are limited by requiring users to fully conceptualize implementation. This article introduces novel formal approach routing single-stranded scaffold that defines shape automated broadens space generates complex multilayer designs in optimally way, based on set constraints desired features. technique computes assemblies utilizing annealing, which is integration grammars simulated annealing algorithm. results presented this illustrate potential code features into